errrrrr, that patent is surely invalid. There have been emulators of hardware video game consoles since before November 2000 - prior art renders the patent invalid.
Whether any of the emulator makers have the balls / cash to take on nintendo when they try and enforce the patent is another matter, but I reckon it'd be an open and shut case....
i guess the only possible angle is that there were not emulators on PDAs and other "low performance" machines before then because they weren't powerful enough - that's very tenuous though, because you could argue that a PDA is exactly the same capability of a laptop of 10 years ago that COULD run the emulators available then...