If it's a Skyscape program, it's best to check with Skyscape. Also try a search, especially in the Medical Pocket PC forum. Here's one thread that reports Skyscape working well under WM5, but it may not be referring exactly to the one you have linked:
http://www.aximsite.com/boards/showt...light=skyscape
There's also a stickied thread on WM5 compatible software stickied to the top of this forum. Have a look. :)